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. 2023 Feb 14;13(2):361. doi: 10.3390/biom13020361

Table 1.

The environmental toxicity values of compound 4a and the pioneering compounds.

Compounds Environmental Toxicity cLog P
Bioconcentration Factors * IGC50 **
Isoindoline-1,3-dione 0.458 2.557 0.536
4-Aminobenzohydrazide 0.495 2.763 −0.753
N-(4-(Hydrazinecarbonyl)phenyl)benzamide 0.469 3.337 1.339
Compound 4a 0.365 3.488 2.674

* The unit of BCF is log10(L/kg). ** 48 h Tetrahymena pyriformis IGC50 (concentration of the test chemical in water in mg/L that causes 50% growth inhibition to Tetrahymena pyriformis after 48 h). The unit of IGC50 is −log10[(mg/L)/(1000 × MW)].