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Schematic illustration of possible anticancer mechanisms responsible for the effects of LMW-AP-FBG against CT-26 colorectal cancer cells. CT-26 bearing mice treated with LMW-AP-FBG showed a significant decrease in PCNA-positive cells and an increase in TUNEL-positive cells in tumor tissue. CT-26 cells treated with LMW-AP-FBG showed anticancer activity by promoting apoptosis through increasing the ratio of Bax/Bcl-xl as well as activated caspase and cytosolic cytochrome c.
