Table 2.
NO SPECS classification of Graves’ Eye Disease *.
| Classification | Signs and Symptoms (Grade) |
|---|---|
| 0 | Asymptomatic, no physical exam findings |
| I | Physical signs only |
| II | Involvement of soft tissue |
| 0: absent | |
| a: minimal | |
| b: moderate | |
| c: marked | |
| III | Proptosis |
| 0: absent | |
| a: minimal: 3 to 4 mm above normal | |
| b: moderate: 5 to 7 mm above normal | |
| c: marked: 8+ mm above normal | |
| IV | Extraocular muscles |
| 0: absent | |
| a: minimal: gaze limitations at extremes | |
| b: moderate: motion restriction, no fixation | |
| c: marked: globe fixation | |
| V | Cornea |
| 0: absent | |
| a: minimal: stippling | |
| b: moderate: ulceration | |
| c: marked: necrosis, perforation, clouding | |
| VI | Optic nerve compression/vision loss |
| 0: absent | |
| a: minimal: 20/20–20/60 vision; disc pallor | |
| b: moderate: 20/70–20/200 vision; disc pallor | |
| c: marked: <20/200 vision; blindness |
* based on table by Werner [34].