Table 2.
Effects of poorly expressed proteins in OS.
| Protein | Decreased Levels in Clinical Sample | Inhibited EMT | Inhibited Cell Migration/Invasion | Inhibited In Vivo Tumor Growth | Inhibited In Vivo Metastasis | Endogenous Function |
|---|---|---|---|---|---|---|
| ARID1a [147] | Yes | Cell Signaling | ||||
| Ezrin [148] | No | Structure | ||||
| FTL [149] | Yes | Metabolism | ||||
| GPER [55] | Yes | Cell Signaling | ||||
| LAIR-1 [150] | Yes | Immune | ||||
| RASSF4 [91] | Yes | Cell Cycle Regulation | ||||
| SOX6 [62] | Yes | Cell Cycle Regulation | ||||
| TSSC3 [49] | Yes | Cell Cycle Regulation | ||||
| WWOX [151] | Yes | Cell Cycle Regulation |
: Significant association; 
: Not studied/reported.