Table 4.
Effects of poorly expressed non-coding ribonucleic acids.
| Ribonucleic Acid | Decreased Levels in Clinical Samples | Inhibited EMT | Inhibited Cell Migration/Invasion | Inhibited In Vivo Tumor Growth | Inhibited In Vivo Metastasis | Associated Pathways/Targets |
|---|---|---|---|---|---|---|
| lncRNA FER1L4 [197,198] | Yes | miR-18a-5p, PI3K/Akt | ||||
| lncRNA GAS5 [199] | Yes | miR-221, ARHI | ||||
| lncRNA MEG3 [200] | Yes | miR-361-5p, FoxM1 | ||||
| lncRNA NKILA [201] | Yes | ↑ | NFκB, Snail | |||
| lncRNA TUSC8 [202] | Yes | miR-197-3p, EHD2 | ||||
| miR-7 [203] | Yes | IGF1R | ||||
| miR-16 [204] | Yes | RAB23 | ||||
| miR-25 [205] | Yes | SOX4 | ||||
| miR-29a [206] | Yes | SOCS1/NFκB, DNMT3B | ||||
| miR-107 [92] | Yes | wnt/β-catenin | ||||
| miR-125a-5p [207] | Yes | MMP11 | ||||
| miR-128 [208] | Yes | Integrin A2 | ||||
| miR-132 [209] | No | SOX4 | ||||
| miR-139-5p [210] | Yes | DNMT1 | ||||
| miR-140-3p [211] | Yes | TRAF6, TGFB | ||||
| miR-145 [51] | Yes | Snail | ||||
| miR-181c [212] | Yes | SMAD7, TGFB | ||||
| miR-203 [213] | Yes | RAB22A | ||||
| miR-331-3p [104] | Yes | MGAT1, Bcl/Bax, wnt/β-catenin | ||||
| miR-342-5p [96] | Yes | wnt/β-catenin | ||||
| miR-363 [214,215] | Yes | PDZD2, NOB1 | ||||
| miR-377-3p [186] | Yes | CuL1, wnt/β-catenin | ||||
| miR-382 [216] | Yes | YB-1 | ||||
| miR-384 [217] | Yes | MECP2, IGFBP3 | ||||
| miR-449a [111] | Yes | EZH2, PI3K/Akt | ||||
| miR-486 [218] | Yes | PIM1 | ||||
| miR-488 [219] | Yes | AQP3 | ||||
| miR-489 [220] | Yes | NAA10 | ||||
| miR-499a [221] | Yes | TGFβ, EGFR, Akt, SHKBP1 | ||||
| miR-503 [222] | No | c-myc | ||||
| miR-506-3p [223] | No | SPHK1, LC3II/I | ||||
| miR-708-5p [65] | No | ZEB1 | ||||
| miR-761 [224] | Yes | ALDH1B1, TGFB | ||||
| miR-765 [117] | Yes | MTUS, ERK | ||||
| miR-CT3 [77] | Yes | p38/MAPK | ||||
| miR-let-7d [225] | No | ↑ | CCND2, E2F2 |
: Significant association; ↑: Inverse association; 
:Not studied/reported.