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Assessment of the malignant growth potential of subclones in nude mice. (A) 100 μM DETANO treated MCF10A parent cells, and the SIT 2-3 clonal population formed small masses in nude mice that were significantly larger than control untreated MCF10A cells. (B) When compared to MB-468 cells alone, MB-468 cells injected with SIT 2-3 cells formed significantly larger tumors. Mice were euthanized at 30 days post-cell injection.
