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. 2023 Feb 15;13(2):371. doi: 10.3390/biom13020371

Figure 2.

Figure 2

MAPK Signaling Is Upregulated in Spaceflight. (a) ERK/MAPK pathways are upregulated in the heart during spaceflight. IPA was used to identify mRNA transcripts predicted to be impacted in hearts from flight and ground control mice; (b,c) Heatmap comparing MAPK-associated transcript expression in flight and ground controls; (d,e) MAPK-related transcripts were significantly induced while in spaceflight (p < 0.001) vs ground controls.