Table 1.
Differential Gene Expression Changes in Oxidative Stress Markers after Spaceflight.
| Gene Symbol | Gene Name | Fold Change |
|---|---|---|
| Cat | Catalase | 1.13 |
| Fancc | Fanconi anemia, complementation group C | 0.82 |
| Gpx1 | Glutathione Peroxidase 1 | 0.78 |
| Gpx3 | Glutathione Peroxidase 3 | 0.27 |
| Gsr | Glutathione reductase | 1.00 |
| Gstp1 | Glutathione S-transferase, pi 1 | 0.83 |
| Ncf2 | Neutrophil cytosolic factor 2 | 0.78 |
| Nox1 | NADPH oxidase 1 | 0.65 |
| Nox4 | NADPH oxidase 4 | 0.49 |
| Prdx1 | Peroxiredoxin 1 | 1.06 |
| Prdx6 | Peroxiredoxin 6 | 1.05 |
| Prnp | Prion protein | 1.02 |
| Ptgs2 | Prostaglandin-endoperoxide synthase 2 | 0.22 |
| Slc41a3 | Solute carrier family 41, member 3 | 1.62 |
| Sod1 | Superoxide dismutase 1 | 0.87 |
| Sod2 | Superoxide dismutase 2 | 1.05 |
| Sod3 | Superoxide dismutase 3 | 0.78 |
| Tpo | Thyroid peroxidase | 1.00 |
| Txnip | Thioredoxin interacting protein | 0.88 |
| Txnrd3 | Thioredoxin reductase 3 | 0.98 |
| Xpa | Xeroderma pigmentosum, complementation group A | 0.72 |
Listed in the table are 21 genes that have been linked to the oxidative stress pathway. These genes show no significant regulation in stress response after 30 days of spaceflight, as defined by a p-value greater than 0.05.