Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 18;13(2):394. doi: 10.3390/biom13020394

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

First examples of CYP promiscuity reported in the diterpenoid metabolism: (a) Diterpenoid substrates of CYP720B4 of sitka spruce. All compounds are attacked on C18 whether as methyl, alcohol, aldehyde substituent: 1: abietadiene; 2: isopimaradiene; 3: sandaracopimaradiene; 4: pimaradiene; 5: palustradiene; 6: levopimaradiene; 7: neoabietadiene; 8: dehydroabietadiene. (b) Diterpenes susbstrates of CYP76M8 of rice. Position of oxidative attack on each compound is numbered and indicated by the red arrow. Via these reactions CYP76M8 contributes to the phytocassane, oryzalexin and momilactone pathways: 1: ent-cassa-12,15-diene; 2: ent-pimara-8(14),15-diene; 3: ent-(iso)kaurene; 4: pimara-8(14),15-diene; 5: ent-sandaracopimaradiene; 6: syn-pimara-7,15-diene; 7: sandaracopimaradiene.