Figure 3.

(A) UCSC Genome Browser Chip-Seq data showing that TEAD4 binds to the region of uc.147 (chr4:151236383-151236690—GRCh37). (B) Results from the TFBSPred tool demonstrate that, in the region of uc.147, binding sites for TEAD4 (marked in green) are predicted. For the analysis, the chromosome location of lnc-uc.147 (4:150315231(+)—GRCh38) was also used. RNA expression of the TEAD4 transcription factor after its silencing in the HepG2 (C), BT-474 (D), and CAMA-1 (E) cells. Expression of lnc-uc.147 after transcription factor silencing in HepG2 (F), BT-474 (G), and CAMA-1 (H) cells. Data normalized by the endogenous controls GAPDH/U6/TBP and the negative control. Three independent experiments are represented. Statistical differences were evaluated using the Student t-test. * p < 0.05.