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. 2023 Jan 20;11(2):291. doi: 10.3390/biomedicines11020291
ACE Angiotensin Converting Enzyme
ADA American Diabetes Association
ADVANCE Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation
ARBs Angiotensin II Receptor Blockers
AWARD-7 A Study Comparing Dulaglutide with Insulin Glargine on Glycemic Control in Participants with Type 2 Diabetes and Moderate or Severe Chronic Kidney Disease
ASCVD Atherosclerotic Cardiovascular Disease
BENEDICT Bergamo Nephrologic Diabetic Complications
BP Blood Pressure
CANVAS Canagliflozin Cardiovascular Assessment
CKD Chronic Kidney Disease
CI Confidence Interval
CREDENCE Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in participants with Diabetic Nephropathy
CRISPR Clustered Regularly Interspaced Short Palindromic Repeats
DAPA-CKD Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients with Chronic Kidney Disease
DECLARE-TIMI Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
DN Diabetic Nephropathy
DPP-4 Dipeptidyl Peptidase 4
DPP-4is Dipeptidyl Peptidase 4 inhibitors
EASD European Association for the Study of Diabetes
eGFR estimated Glomerular Filtration Rate
ELIXA Evaluation of Lixisenatide in Acute Coronary Syndrome
EMPA-KIDNEY The Study of Heart and Kidney Protection with Empagliflozin, study of heart protection and kidneys with Empagliflozin
EMPA-REG Empagliflozin cardiovascular outcome events in T2DM patients
ESRD End-Stage Renal Disease
EXSCEL Exenatide Study of Cardiovascular Event Lowering
FIDELIO-DKD Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease
FIGARO-DKD Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic kidney Disease
FLOWA Research Study to See How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease
GFR Glomerular Filtration Rate
GLP-1 Glucagon-Like Peptide-1
GLP-1 Ras Glucagon-Like Peptide-1 Receptor Agonists
HbA1c Hemoglobin A1c
HR Hazard Ratio
KIDNEY The Study of Heart and Kidney Protection with Empagliflozin
ICAM1 Intercellular Adhesion Molecule 1
LDL-C Low-Density Lipoproteins Cholesterol
LEADER Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results-A Long Term Evaluation
MACE Major Adverse Cardiovascular Events
MRA Mineralocorticoid Receptor Antagonist
NHE3 Sodium Hydrogen Exchanger 3
NSAIDs Nonsteroidal Anti-Inflammatory Drugs
PCSK9 ProproteinConvertase Subtilisin/Kexin type 9
PIONEER-6 Cardiovascular Safety of Oral Semaglutide in Subjects with Type 2 Diabetes
RAS Renin-Angiotensin System
RASS Renin-Angiotensin System Study
RCTs Randomized Controlled Trials
REWIND Researching Cardiovascular Events with a Weekly Incretin in Diabetes
ROADMAP Randomized Olmesartan and Diabetes Microalbuminuria Prevention
ROS Reactive Oxygen Species
RRT Renal Replacement Therapy
SGLT-2is Sodium Glucose Cotransporter 2 inhibitors
SUSTAIN-6 Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes Cardiovascular Outcome
T2DM Type 2 Diabetes Mellitus
UACR Urinary Albumin-To-Creatinine Ratio
VCAM1 Vascular Cell Adhesion Molecule 1
VLDL Very Low-Density Lipoprotein