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Chemical structures of lansoprazole, astemizole, and their labeled derivatives. (a): lansoprazole, (b): astemizole, (c): N-methyl-lansoprazole (NML), (d): [11C]-N-methyl-lansoprazole ([11C]NML), (e): [18F]-N-methyl-lansoprazole ([18F]NML), (f): astemizole-based radiotracers, R = 11CH3, 18FCH2CH2.
