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. 2023 Jan 31;13(2):266. doi: 10.3390/biom13020266

Figure 2.

Figure 2

Schematic representation of pathogenesis of three diseases characterized by parietal epithelial cell activation- classical focal segmental glomerulosclerosis, collapsing glomerulopathy, and crescentic glomerulonephritis. FSGS—focal segmental glomerulosclerosis; CG—collapsing glomerulopathy; CrescGN—crescentic glomerulonephritis; PEC—parietal epithelial cell; PD—podocyte; GBM—glomerular basement membrane; BS—Bowman’s space; CL—capillary lumen; aPECs—activated parietal epithelial cells.