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. 2023 Feb 20;11(2):641. doi: 10.3390/biomedicines11020641

Figure 1.

Figure 1

FDA-approved drugs for the treatment of acute myeloid leukemia (AML). The structure of standard chemotherapies—cytarabine, anthracyclines such as daunorubicin or idarubicin, and the small molecule FDA-approved drugs—included IDH inhibitors, FLT3 inhibitors, BCL-2 inhibitors, hypomethylating agents, and CPX-351. Abbreviations: DNA: deoxyribonucleic acid; IDH1/2: isocitrate dehydrogenase ½; FLT3: FMS like tyrosine kinase 3; BCL-2: B-cell lymphoma 2; BMS: Bristol Myers Squibb.