Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Non-approved small molecule inhibitors for acute myeloid leukemia (AML). In addition to the FDA-approved drugs, some other FLT3 inhibitors are currently in clinical trials. Sorafenib is a multi-targeted tyrosine kinase inhibitor, and quizartinib is a specific FLT3 inhibitor. These have not been approved by the FDA for use in AML. Abbreviations: FLT3: FMS-like tyrosine kinase 3; HDAC: histone deacetylase; CDK9: cyclin dependent kinase 9.
