Table 5.
Statistical data (results of mixed ANOVA) of open-field test (Experiment 2) in male and female, control and 3xTg-AD mice. The corresponding data are presented on Figure 5. Repeated measurements were conducted in 11-month-old animals during 30 min open-field test. Significant main effects are highlighted in red.
| Degree of Freedom | F | p | |
|---|---|---|---|
| Distance travelled (cm) | |||
| Genotype | 1, 26 | 43.003 | 0.000 |
| Sex | 1, 26 | 1.940 | 0.175 |
| Genotype × Sex | 1, 26 | 0.030 | 0.865 |
| Time | 5, 130 | 0.963 | 0.443 |
| Genotype × Time | 5, 130 | 0.425 | 0.831 |
| Sex × Time | 5, 130 | 1.781 | 0.101 |
| Genotype × Sex × Time | 5, 130 | 1.031 | 0.402 |
| Time spent in centrum (%) | |||
| Genotype | 1, 26 | 8.939 | 0.007 |
| Sex | 1, 26 | 7.856 | 0.010 |
| Genotype × Sex | 1, 26 | 0.572 | 0.457 |
| Time | 5, 130 | 11.730 | 0.000 |
| Genotype × Time | 5, 130 | 5.880 | 0.000 |
| Sex × Time | 5, 130 | 1.753 | 0.129 |
| Genotype × Sex × Time | 5, 130 | 1.610 | 0.163 |