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. 2023 Feb 7;12(4):533. doi: 10.3390/cells12040533

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Intermittent fasting induced significant changes in the hepatic expression of genes involved in lipid and cholesterol metabolism only in males fed CD. (A,B) Expression of genes related to lipolysis in ad libitum (AL) or intermittent fasting (IF) CD-fed males (A) and HFCD-fed males (B). (C,D) Expression of genes related to lipogenesis in ad libitum (AL) or intermittent fasting (IF) CD-fed males (C) and HFCD-fed males (D). (E,F) Expression of genes related to cholesterol synthesis in ad libitum (AL) or intermittent fasting (IF) CD-fed males (E) and HFCD-fed males (F). (G,H) Expression of genes related to cholesterol transport in ad libitum (AL) or intermittent fasting (IF) CD-fed males (G) and HFCD-fed males (H). Values are expressed as means ± SEM (n = 5–8 per group); * p < 0.05, ** p < 0.01, *** p < 0.001.