Table 4.

Rates of severe toxicities, upfront dose reduction and access to second line treatment according to CGA category and onco-MPI risk groups (% of pts).

N. Patients Receiving First Line CT	FIT (32 pts)	Vulnerable (36 pts)	Frail (8 pts)	Intermediate Risk (12 pts)	High Risk (63 pts)
G3-G4 Toxicity	40.6%	33.3%	51.1%	58.3%	36.5%
Upfront Dose Reduction	34.4%	44.4%	42.8%	66%	39.4%
Dose Reduction due to Toxicity	12.5%	8.3%	12.5%	33.3%	15.8%
Second Line CT	38.4%	34.7%	12.5%	66%	58.7%

Legend: CGA = Comprehensive geriatric assessment; CT = Chemotherapy; G3–G4 = Grade 3 or 4 according to Common Terminology Criteria for Adverse Events.