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. 2023 Feb 7;15(4):1043. doi: 10.3390/cancers15041043

Table 6.

Univariate analysis and multivariate analysis for one-year survival.

Univariate Analysis
Variable HR Confidence Interval p Value
Sex M 1.481 0.822 2.667 0.191
Histology Leiomyosarcoma 0.633 0.306 1.309 0.218
Age 75–80 0.641 0.322 1.280 0.208
Age ≥80 0.710 0.356 1.416 0.331
Location metastasis Lung 0.761 0.387 1.496 0.428
Location of primary tumour Retroperitoneum 1.687 0.852 3.341 0.134
Location of primary tumour Other 2.086 1.017 4.275 0.045
PS at metastatic disease ≥2 2.754 1.526 4.971 <0.001
Comorbidity grade according to CIRS 3–4 1.043 0.502 2.171 0.91
Onco-MPI High-risk 4.743 1.150 19.56 0.03
First line chemotherapy Yes 0.193 0.106 0.354 <0.001
Multivariate Analysis
Variable HR Confidence Interval p Value
Sex Male 1.4579 0.666 3.188 0.3450
Histology Leiomyosarcoma 0.5210 0.211 1.287 0.1574
Age ≥80 0.3968 0.174 0.906 0.0283
Age 75–80 0.5406 0.249 1.175 0.1203
Location of metastasis Lung 0.5860 0.268 1.280 0.1802
Location of primary tumour Extremities/trunk 2.0642 0.952 4.478 0.0666
Location of primary tumour Other 2.2186 0.959 5.129 0.0624
PS at metastatic disease ≥2 2.0196 0.889 4.586 0.093
Comorbidity grade according to CIRS 3–4 0.8535 0.366 1.989 0.7136
First line chemotherapy YES 0.2405 0.113 0.512 0.0002
Onco-MPI High-risk 5.5682 1.251 24.793 0.0242

Legend: CGA = Comprehensive geriatric assessment; CIRS = Cumulative illness rating scale ECOG = Eastern cooperative oncology group; PS = Performance status.