Table 2.
Comparison and logistic regression analysis of biochemical data between the PSF and no-PSF groups.
| Laboratory Parameters | PSF Group | No-PSF Group | p | |||
|---|---|---|---|---|---|---|
| Lesion location, n (%) | 0.032 * | |||||
| Cerebral cortex | 10 (13.7) | 28 (17.8) | ||||
| Limbic system | 6 (8.2) | 16 (10.2) | ||||
| Basal ganglia | 32 (43.8) | 67 (42.7) | ||||
| Cerebellum | 15 (20.5) | 25 (15.9) | ||||
| Brainstem | 10 (13.7) | 21 (13.4) | ||||
| Anxiety (HAMA score ≥ 7), n (%) | 38 (52.1) | 36 (22.9) | <0.001 * | |||
| Depression (HADA score ≥ 7), n (%) | 41 (56.2) | 42 (26.8) | <0.001 * | |||
| Cognitive impairment (MoCA score < 26), n (%) | 36 (49.3) | 59 (37.6) | 0.677 | |||
| Sleep disorders (PSQI), mean (SD) | 11.4 (4.3) | 7.4 (3.6) | <0.001 * | |||
| FPG, mean (SD), mmol/L | 8.85 (1.96) | 5.86 (1.65) | <0.001 ** | |||
| TG, mean (SD), mmol/L | 1.72 (0.76) | 1.66 (0.74) | 0.563 | |||
| TC, mean (SD), mmol/L | 5.23 (1.09) | 5.02 (1.01) | 0.647 | |||
| LDL-C, mean (SD), mmol/L | 3.30 (0.89) | 2.96 (0.83) | 0.450 | |||
| HDL-C, mean (SD), mmol/L | 1.12 (0.27) | 1.11 (0.29) | 0.797 | |||
| UA, mean (SD), µmol/L | 285.67 (80.70) | 332.11 (82.68) | <0.001 ** | |||
| FIB, mean (SD), g/L | 3.55 (0.81) | 3.50 (0.80) | 0.374 | |||
| HCY, mean (SD), μmol/L | 24.64 (8.47) | 16.32 (6.06) | <0.001 ** | |||
| FT4, mean (SD), pmol/L | 17.22 (4.13) | 16.89 (3.79) | 0.342 | |||
| TSH, mean (SD), µU/mL | 3.00 (1.56) | 2.58 (1.26) | 0.278 | |||
| Variables | β | SE3 | Wald χ2 | p | OR | 95% CI |
| Female sex | 0.897 | 0.294 | 4.524 | 0.030 | 2.12 | 1.14–3.94 |
| Sleep disorders | 0.265 | 0.142 | 6.020 | 0.010 | 1.50 | 1.01–1.73 |
| Depressive state | 0.398 | 0.138 | 5.686 | 0.002 | 1.58 | 1.01–1.98 |
HAMA, Hamilton Anxiety Scale; HAMD, Hamilton Depression Rating Scale; MoCA, Montreal Cognitive Assessment; PSQI, Pittsburgh Sleep Quality Index; SD, standard deviation; FPG, fasting plasma glucose; TG, triglyceride; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; UA, uric acid; FIB, fibrinogen; HCY, homocysteine; FT4, free thyroxine; TSH, thyroid-stimulating hormone; SD, standard deviation; SE, standard error; OR, odds ratio; CI confidence interval. * p < 0.05; ** p < 0.001.