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. 2023 Feb 18;12(4):657. doi: 10.3390/cells12040657
AJ adherens junction
AMPK AMP-activated protein kinase
ApoE apolipoprotein E
ARE antioxidant response element
BBB blood–brain barrier
bEnd.3 murine brain endothelial cell line
COX2 cyclooxygenase 2
CNS central nervous system
ERK1/2 extracellular-signal-regulated kinase 1/2
GCLC glutamate-cysteine ligase catalytic subunit
GCLM glutamate-cysteine ligase regulatory subunit
GJ gap junctions
GPR G protein-coupled receptor
HAT histone acetylase
HDAC histone deacetylase
hCMEC/D3 human cerebral microvascular endothelial cell line
H3K9/14 histone
H3 acetylated in lysine 9/14
HO-1 heme oxygenase 1
i.g. intragastrically
IL-1β interleukin 1-β
iNOS inducible NO-synthase
i.p. intraperitoneally
JAM junction adhesion molecule
JNK1/2 C-Jun N-terminal kinase
Keap1 Kelch-like ECH-associated protein 1
LPS lipopolysaccharide
NF- κB nuclear factor kappa B
Nlrp3 NOD-like receptor family pyrin domain containing 3
NQO1 NAD(P)H:quinone oxidoreductase-1
Nrf2 nuclear erythroid 2-related factor 2
NVU neurovascular unit
MCAO middle cerebral artery occlusion
MCT monocarboxylate transporter
MMP metalloproteinase
PPARγ peroxisome proliferator-activated receptor gamma
SB sodium butyrate
SCFA short-chain fatty acid
SOD1 superoxide dismutase 1
T2DM type 2 diabetes mellitus
TEER transendothelial electrical resistance
TJ tight junction
TNFα tumor necrosis factor alpha
ZO zonula occludens