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. 2023 Feb 14;12(4):612. doi: 10.3390/cells12040612

Figure 4.

Figure 4

Co-administration of Curcumin with Lenvatinib induced cellular apoptosis via intracellular accumulation of ROS. (A) Representative images of oxidase stress assay following treatment in Lenvatinib-resistant cells (*: p < 0.05 vs. control, #: p < 0.05 vs. Lenvatinib, %: p < 0.05 vs. Curcumin). (B) Representative images of annexin-V assays. Graphs indicate the percentages of live and apoptotic cells (*: p < 0.05 vs. control, #: p < 0.05 vs. Lenvatinib, %: p < 0.05 vs. Curcumin). The data indicate mean (column) ± SD values. ROS, reactive oxygen species; SD, standard deviation.