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. 2023 Feb 5;15(4):1012. doi: 10.3390/cancers15041012

Table 4.

Association of BCL2-938 C > A gene variation in cases and controls.

Genotypes Control
n = 105
Cases
n = 100
OR (95% CI) RR (95% CI) p
Codominant inheritance model
BCL2–CC 57 37 1.00 (ref.) 1 (ref.)
BCL2–CA 42 58 2.12 (1.19–3.77) 1.44 (1.08–1.91) 0.009
BCL2–AA 06 05 1.28 (0.36–4.51) 1.11 (0.63–1.95) 0.069
Dominant inheritance model
BCL2–CC 57 37 1.00 (ref.) 1 (ref.)
BCL2 (CA + AA) 48 63 2.02 (1.15–3.53) 1.40 (1.07–1.83) 0.013
Recessive inheritance model
BCL2 (CC + CA) 99 95 1.00 (ref.) 1 (ref.)
BCL3–AA 06 05 0.88 (0.25–2.94) 0.93 (0.53–1.63) 0.82
Allele
BCL2–C 156 132 1.00 (ref.) 1 (ref.)
BCL2–A 54 68 1.48 (0.97–2.28) 1.22 (0.97–1.53) 0.06
Overdominant inheritance model
BCL2-CA 42 58 1.00 (ref.) 1 (ref.)
BCL2-CC + AA 63 42 0.48 (0.28–0.84) 0.70 (0.53–0.92) 0.012

Abbreviations: OR, odds ratio; RR, relative risk ratio.