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. 2023 Feb 5;15(4):1012. doi: 10.3390/cancers15041012

Table 7.

Association of BIRC5-rs 9904341 G > C gene variation in cases and controls.

Genotypes Controls
n = 105
Cases
n = 100
OR (95% CI) RR (95% CI) p
Codominant inheritance model
BIRC5-GG 70 29 1.00 (ref.) 1.00 (ref.)
BIRC5-GC 50 66 3.18 (1.80–5.62) 1.64 (1.28–2.09) 0.001
BIRC5-CC 02 05 6.0 (1.10–32.9) 2.47 (0.76–8.03) 0.037
Dominant inheritance model
BIRC5-GG 70 29 1.00 (ref.) 1.00 (ref.)
BIRC5-(GC + CC) 52 71 3.29 (1.87–5.77) 1.67 (1.31–2.13) 0.001
Recessive inheritance model
BIRC5-(GG + GC) 120 95 1.00 (ref.) 1.00 (ref.)
BIRC5-CC 02 05 3.15 (0.59–16.6) 1.95 (0.60–6.34) 0.17
Allele
BIRC5-G 190 124 1.00 (ref.) 1.00 (ref.)
BIRC5-C 57 76 2.04 (1.35–3.08) 1.30 (1.03–1.63) 0.001
Overdominant inheritance model
BIRC5-GC 50 66 1.00 (ref.) 1.00 (ref.)
BIRC5-GG + CC 72 34 0.35 (0.20–0.61) 0.88 (0.64–1.23) 0.002

Abbreviations: OR, odds ratio; RR, relative risk ratio.