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. 2022 Apr 5;206(1):44–55. doi: 10.1164/rccm.202106-1439OC

Table 1.

Baseline Characteristics of Canadian Cohort Obstructive Lung Disease Study Participants*

Characteristic Total (N = 1452) COPD (n = 691; 47.6%) Non-COPD (n = 761; 52.4%)
Sociodemographic factor      
 Sex, n (%)      
  Male 815 (56.1) 412 (59.6) 403 (53.0)
  Female 637 (43.9) 279 (40.4) 358 (47.0)
 Age, mean (SD), yr 66.6 (9.8) 67.3 (10.1) 66.0 (9.5)
 BMI, mean (SD), kg/m2 27.7 (5.3) 27.5 (5.31) 27.8 (5.24)
 Education, n (%)      
  No postsecondary 328 (22.6) 179 (25.9) 149 (19.6)
  Some postsecondary 1124 (77.4) 512 (74.1) 612 (80.4)
Tobacco and biomass smoke exposure      
 Tobacco status, n (%)      
  Never smoker 514 (35.4) 192 (27.8) 322 (42.3)
  Ex-smoker 718 (49.4) 370 (53.5) 348 (45.7)
  Current smoker 220 (15.2) 129 (18.7) 91 (12.0)
 Pack-years smoking, mean (SD) 26.1 (23.8) 31.6 (24.3) 19.8 (21.6)
 Environmental tobacco smoke, n (%)      
  Never 836 (57.6) 370 (53.5) 466 (61.2)
  Ever 616 (42.4) 321 (46.5) 295 (38.8)
 Lifetime biomass exposure, n (%), yr      
  <10 1249 (86.0) 596 (86.3) 653 (85.8)
  ⩾10 203 (14.0) 95 (13.7) 108 (14.2)
Respiratory health      
 FEV1, L 2.55 (0.81) 2.33 (0.78) 2.76 (0.77)
 FEV1 (% predicted) 91.7 (20.2) 82.3 (19.3) 100 (17.1)
 FVC, L 3.68 (1.07) 3.78 (1.11) 3.59 (1.02)
 FVC (% predicted) 99.0 (17.2) 100 (17.9) 97.8 (16.4)
 FEV1/FVC (%) 69.5 (10.3) 61.1 (8.14) 77.1 (4.63)
 Airflow limitation severity, n (%)      
  Mild (GOLD 1) 388 (56.2) N/A
  Moderate (GOLD 2) 264 (38.2) N/A
  Severe (GOLD 3) 38 (5.5) N/A
  Very severe (GOLD 4) 1 (0.1) N/A
 Respiratory medication, n (%)      
  None 1124 (77.4) 446 (64.5) 678 (89.1)
  ⩾1 328 (22.6) 245 (35.5) 83 (10.9)
 Asthma, n (%)      
  Nonasthmatic 1107 (76.2) 470 (68.0) 637 (83.7)
  Asthmatic 345 (23.8) 221 (32.0) 124 (16.3)
 Childhood hospitalization for respiratory illness, n (%)      
  No 1352 (93.2) 630 (91.3) 722 (94.9)
  Yes 99 (6.8) 60 (8.7) 39 (5.1)
  Missing 1 1 0
Dysanapsis      
 Airway-to-lung ratio      
  Fourth quartile (highest) 296 (24.3) 87 (14.6) 209 (33.5)
  Third quartile 305 (25.0) 117 (19.6) 188 (30.2)
  Second quartile 305 (25.0) 165 (27.7) 140 (22.5)
  First quartile (lowest) 313 (25.7) 227 (38.1) 86 (13.8)
  Missing 233 95 138

Definition of abbreviations: BMI = body mass index; COPD = chronic obstructive pulmonary disease; GOLD = Global Initiative for Chronic Obstructive Lung Disease; N/A = not applicable.

*

For 1,452 participants with complete data for baseline age, BMI, education, tobacco status, pack-years smoking, environmental tobacco smoke at home, biomass fuel exposure, respiratory medication intake, spirometry, and ambient nitrogen dioxide exposure.