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. 2023 Feb 9;12(4):564. doi: 10.3390/cells12040564

Table 2.

Derived cfDNA parameters, heart rate parameters and subjective appraisal with respect to conditions.

Healthy Men (n = 29)
Resting
Condition		 TSST Dependent t-Test
Derived cfDNA Parameters M SD M SD t p
Peak 14.25 4.58 17.92 7.08 −2.914 ≤0.01 **
(d = −0.54)
Delta Peak-Baseline 4.75 2.92 9.23 5.10 −4.192 ≤0.001 ***
(d = −0.78)
AUCI 102.17 260.75 306.70 198.08 −3.712 ≤0.001 **
(d = −0.69)
Derived cortisol parameters
Peak a) 63.09 17.90 94.34 23.26 −7.046 ≤0.001 ***
(d = −1.33)
Delta Peak-Baseline a) 10.74 8.69 42.35 25.87 −6.471 ≤0.001 ***
(d = −1.22)
AUCI a) −1168.22 1299.72 930.13 2457.85 −3.927 ≤0.001 ***
(d = −0.74)
Derived heart rate parameters
Peak b) 70.44 11.64 100.59 18.85 −7.584 ≤0.001 ***
(d = −1.58)
Delta Peak-Baseline b) 0.88 3.20 31.04 20.20 −7.584 ≤0.001 ***
(d = −1.58)
Subjective Appraisal
PASA Threat, (1–6) 1.47 0.83 3.09 1.08 −7.855 ≤0.001 ***
(d = −1.46)
Challenge, (1–6) 2.35 0.96 4.07 0.79 −8.100 ≤0.001 ***
(d = −1.50)
Self concept, (1–6) 4.55 0.89 3.91 1.02 2.660 ≤0.05 *
(d = 0.49)
Control expectancy, (1–6) 4.63 0.73 4.31 0.84 2.002 0.055
(d = 0.49)
Primary appraisal, (1–6) 1.91 0.79 3.58 0.82 −9.529 ≤0.001 ***
(d = −1.77)
Secondary appraisal, (1–6) 4.59 0.64 4.11 0.79 3.143 ≤0.001 ***
(d = 0.58)
PASA—Stress index −2.68 1.28 −0.54 1.39 −7.663 ≤0.001 ***
(d = −1.41)
VAS 41.35 11.23 58.51 9.42 −8.903 ≤0.001 ***
(d = −1.65)

AUCI area under the curve with respect to increase, M Mean, PASA Primary Appraisal Secondary Appraisal, SD Standard Deviation, VAS Visual Analogue Scale. a) Sub-sample of n = 29 participants b) Sub-sample of n = 23 participants. *: p ≤ 0.05, **: p ≤ 0.01, ***: p ≤ 0.001.