Figure 6.
TEMRA cell subsets based on the expression of CD57 and CD28. (A): CD8+ TEMRA cells in healthy donors were divided into four subsets based on the expression of CD57 and CD28. They are depicted as percentages of CD8+ TEMRA cells. Individuals with CMV seropositivity are depicted in red (n = 10) and individuals that are seronegative for CMV are depicted in blue (n = 11). (B): CD8+ TEMRA cells in patients before RT were divided into four subsets based on the expression of CD57 and CD28. They are depicted as percentages of CD8+ TEMRA cells. Individuals with CMV seropositivity are depicted in red (n = 11) and individuals that are seronegative for CMV are depicted in blue (n = 13). (C): CD4+ TEMRA cells in healthy donors were divided into four subsets based on the expression of CD57 and CD28. They are depicted as percentages of CD4+ TEMRA cells. Individuals with CMV seropositivity are depicted in red (n = 10) and individuals that are seronegative for CMV are depicted in blue (n = 11). (D): CD4+ TEMRA cells in patients before RT were divided into four subsets based on the expression of CD57 and CD28. They are depicted as percentages of CD4+ TEMRA cells. Individuals with CMV seropositivity are depicted in red (n = 11) and individuals that are seronegative for CMV are depicted in blue (n = 13). For the statistical analysis, a non-parametric two-tailed Mann–Whitney U-test was used (*: p < 0.05; **: p < 0.01; ***: p < 0.001; ****: p < 0.0001).