AIF	apoptosis-inducing factor
APAF1	apoptotic protease-activating factor 1
APC	antigen-presenting cell
ASC	adapter protein apoptosis-associated speck-like protein containing a CARD
ASCO	apoptosis-associated speck-like protein containing a caspase recruitment domain
ATM	ataxia telangiectasia mutated (A-T mutated)
ATR	ataxia telangiectasia and Rad3-related
ATRIP	ATR-interacting protein
BCL-2	apoptosis regulator BCL2
BCL-xL	B-cell lymphoma-extra large
CDC25A/C	M-phase inducer phosphatases
CDK	cyclin-dependent kinase
CHK1/2	checkpoint kinases
CL	Cardiolipin
CRT	Calreticulin
CXCL	C-X-C motif chemokine receptors
DAMPs	damage-associated molecular patterns
DDR	DNA damage response
DFNA5	deafness, autosomal dominant 5, isoform CRA
DIABLO	direct inhibitor of apoptosis-binding protein with low
DNA-PKcs	DNA-dependent protein kinase catalytic subunit
DOX	Doxorubicin
DPC	DNA–protein crosslink
DR5	death receptor 5
DSBs	double-strand breaks
eEF-2K	eukaryotic elongation factor-2 kinase
EMT	epithelial–mesenchymal transition
ER	Endoplasmic reticulum
ETAA1	Ewing’s tumor-associated antigen 1
ETC	electron transport chain
FASL	FAS antigen ligand
FDA	Food and Drug Administration
FLIP	FLICE/caspase-8 inhibitory protein
GATA4	GATA Binding Protein 4
GPX4	glutathione peroxidase
GSDMD/E	gasdermin-D/E
GZMA/B	granzyme A/B
HMGB1	high mobility group box protein B1
HR	homologous recombination
IFNs	Interferons
ILs	Interleukins
IREs	iron-response elements
IRF1	interferon regulatory factor 1
IRP1/2	iron regulatory proteins 1/2
JAK	tyrosine-protein kinase JAK
JNK	C-Jun N-terminal kinase
MAVS	adaptor protein mitochondrial antiviral signaling
MCM2/7	minichromosome maintenance helicase complex
MDA-5	melanoma differentiation Ag-5
MDC-1	mediator of DNA damage checkpoint protein 1
MDR1	multidrug resistance 1
MHC	major histocompatibility complex
MRE11	meiotic recombination 11 homolog 1
MRN	MRE11–RAD50–NBS1 complex
mtDNA	mitochondrial DNA
NBS1	Nibrin
nDNA	nuclear DNA
NFAT	nuclear factor of activated T-lymphocytes
NF-κB	nuclear factor kappa-light-chain-enhancer of activated B cells
NHEJ	non-homologous end joining
NK	natural killer cell
NLRP3	NACHT, LRR, and PYD domains-containing protein 3
NOXA	phorbol-12-myristate-13-acetate-induced protein 1
NRF2	nuclear factor erythroid 2-related factor 2
P2RX7	P2X purinoceptor
PARP-1	poly(ADP-ribose) polymerase 1
PARs	poly(ADP-ribose) polymers
PD-L1	programmed death ligand 1
PEG	polyethylene glycol
PFNs	Perforins
PG-P	P-glycoprotein
PIKKs	phosphoinositide 3-kinase-related protein kinases
PNKP	polynucleotide kinase phosphatase
pRB	retinoblastoma protein
PRDX2	peroxiredoxin-2
PUMA	isoform 1 of Bcl-2-binding component 3, isoforms 1/2
RHINO	RAD9, RAD1, HUS1 interacting nuclear orphan
RIG-1	retinoic acid inducible gene-I
RNS	reactive nitrogen species
ROS	reactive oxygen species
RPA	replication protein A
SASP	senescence-associated secretory phenotype
SOD2	superoxide dismutase 2
SMAC	secondary mitochondria-derived activator of caspases
SSBR	single-strand break repair
SSBs	single-strand breaks
ssDNA	single-stranded DNA
STAT1/2/3	signal transducer and activator of transcription 1/2/3
TAMs	tumor-associated macrophages
TPD-1	tyrosyl-DNA phosphodiesterase 1
TIS	therapy-induced senescence
TLR4	Toll-like receptor 4
TNFR1	tumor necrosis factor receptor 1
TNF-α	tumor necrosis factor α
TOPB1	topoisomerase 2-binding protein 1
TP53	cellular tumor antigen p53
TRAIL	TNF-related apoptosis inducing ligand
TRX1	thioredoxin-1
XRCC1	X-ray repair cross-complementing group-1