Figure 2.

Average perioperative cortisol and ACTH values in CD patients. (A)-(B). No differences in plasma ACTH (A) or cortisol (B) were identified CD patients in remission vs nonremission at the time of extubation. (C) In CD patients, the postoperative ACTH peak was blunted in patients achieving early remission. (D) CD patients achieving early remission also showed lower postoperative cortisol levels. Preoperative cortisol and ACTH levels (C and D) were measured just prior to CRH or DDAVP stimulation testing. Error bars = SEM. Abbreviations: CD, Cushing's disease; DDAVP, desmopressin.