Table 1.
Patient demographics, endocrine characteristics, and result of immunohistochemical staining of resected tumors
| Diagnosis | CD | P-value | Non-CD | P-value* | |
|---|---|---|---|---|---|
| Endocrine remission | Remission | Nonremission | NA | NA | |
| Demographics | |||||
| Number of patients | 90 | 11 | NA | 28 | NA |
| Age in years | 22 (15) | 26 (21) | 0.43 | 44 (16) | <0.01 |
| BMI | 30 (8) | 33 (7) | 0.24 | 31 (6) | 0.88 |
| % Female | 53 | 69 | 0.31 | 46 | 0.4 |
| % White race | 76 | 54 | 0.12 | 48 | 0.02 |
| % re-operations | 10 | 46 | <0.01 | 7 | 0.39 |
| Endocrine characteristics | |||||
| Preoperative cortisol | 15.0 (6.1) | 14.0 (7.6) | 0.62 | 9.3 (4.4) | <0.01 |
| CRH-stimulated cortisol fold change | 0.8 (0.8) | 1.0 (0.4) | 0.19 | NA | NA |
| Preoperative ACTH | 54.1 (64.1) | 38.5 (19.9) | 0.09 | 29.6 (19.6) | <0.01 |
| CRH-stimulated ACTH fold change | 2.4 (3.5) | 2.3 (1.9) | 0.88 | NA | NA |
| Pathology | |||||
| ACTH stain | 90 | 11 | NA | 0 | NA |
| GH | 0 | 0 | NA | 8 | NA |
| PRL | 0 | 0 | NA | 5 | NA |
| Fsh/Lh | 0 | 0 | Na | 13 | Na |
Abbreviations: BMI, body mass index; CD, Cushing’s disease; PRL, prolactin.