Table 2.
Predictors of early nonremission following transsphenoidal surgery
Variable | OR | 95% CI | P-value | Adj OR | Adj 95% CI | Adj P-value |
---|---|---|---|---|---|---|
Age in years | 1.0 | 1.0, 1.0 | 0.39 | 1.0 | 1.0, 1.0 | 0.55 |
BMI | 1.0 | 1.0, 1.1 | 0.22 | 1.0 | 1.0, 1.1 | 0.41 |
% Female | 2.0 | 0.6, 6.9 | 0.29 | 1.8 | 0.5, 6.6 | 0.35 |
% White race | 0.4 | 0.1, 1.2 | 0.10 | 0.4 | 0.1, 1.5 | 0.17 |
Preoperative cortisol | 1.0 | 0.8, 1.1 | 0.55 | 1.0 | 0.8, 1.1 | 0.63 |
0-hour cortisol | 1.0 | 1.0, 1.1 | 0.11 | 1.0 | 1.0, 1.1 | 0.19 |
6-hour cortisol | 1.0 | 1.0, 1.1 | 0.01 | 1.0 | 1.0, 1.1 | 0.02 |
12-hour cortisol | 1.1 | 1.0, 1.1 | 0.01 | 1.1 | 1.0, 1.1 | 0.02 |
NEPV 0-hour cortisol | 1.1 | 1.0, 1.1 | 0.03 | 1.1 | 1.0, 1.2 | 0.03 |
NEPV 6-hour cortisol | 1.1 | 1.0, 1.1 | 0.01 | 1.2 | 1.0, 1.3 | 0.02 |
NEPV 12-hour cortisol | 1.1 | 1.0, 1.3 | 0.01 | 1.2 | 1.0, 1.3 | 0.01 |
Preoperative ACTH | 1.0 | 1.0, 1.0 | 0.50 | 1.0 | 1.0, 1.0 | 0.58 |
0-hour ACTH | 1.0 | 1.0, 1.0 | 0.02 | 1.0 | 1.0, 1.0 | 0.07 |
6-hour ACTH | 1.0 | 1.0, 1.0 | 0.10 | 1.0 | 1.0, 1.0 | 0.28 |
12-hour ACTH | 1.0 | 1.0, 1.0 | 0.04 | 1.0 | 1.0, 1.0 | 0.13 |
NEPV 0-hour ACTH | 1.0 | 1.0, 1.0 | 0.06 | 1.0 | 1.0, 1.0 | 0.04 |
NEPV 6-hour ACTH | 1.0 | 1.0, 1.0 | 0.02 | 1.0 | 1.0, 1.0 | 0.02 |
NEPV 12-hour ACTH | 1.0 | 1.0, 1.0 | 0.15 | 1.0 | 1.0, 1.0 | 0.16 |
Results of univariable logistic regression with nonremission as the dependent variable or multivariable logistic regression adjusting for age, female gender, and White race.
Abbreviations: Adj, adjusted; BMI, body mass index; NEPV, normalized early postoperative values; OR, odds ratio.