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. 2023 Feb 17;30(2):2429–2440. doi: 10.3390/curroncol30020185

Table 1.

Hereditary genomic mutation risk rates for developing breast and/or ovarian cancer.

Gene Ovarian Cancer Cumulative Risk (by Age ≥ 70) Breast Cancer Cumulative Risk (by Age ≥ 70)
MLH1 4–20% Unknown
MSH2 8–38% Unknown
MSH6 1–13% Unknown
PALB2 Unknown 35%
ATM Unknown 33%
STK11 18–21% 45–50%
BRIP1 7–10% Unknown
RAD51C/D 5–12% Unknown
BRCA1 45–60% 65–80%
BRCA2 11–35% 50–70%