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. 2023 Feb 24;18(2):e0281701. doi: 10.1371/journal.pone.0281701

Table 3. Stepwise logistic regression analysis showing factors associated with coronary atherosclerosis in different models.

Odds Ratio (OR) 95% CI for OR P-value
Lower Upper
Model 1: Inclusion of traditional cardiovascular risk factors only
Dyslipidemia 3.30 1.41 7.77 0.006
CD4:CD8 ratio 0.21 0.07 0.68 0.009
Hypertension 2.56 1.09 6.04 0.031
AUC: 0.7465 (95%CI: 0.6514–0.8416)
Model 2: Inclusion of retinal characteristics only
Left MBCA 0.69 0.46 1.04 0.079
Right CRVE 2.16 1.10 4.24 0.025
Right adjusted CRAE 0.32 0.15 0.65 0.002
Right MV asymmetry 0.58 0.36 0.92 0.020
AUC: 0.7298 (95%CI: 0.6356–0.8241)
Model 3: Inclusion of traditional cardiovascular risk factors and retinal characteristics retinal characteristics
Dyslipidemia 3.27 1.31 8.17 0.011
CD4:CD8 ratio 0.23 0.07 0.79 0.019
Hypertension 2.23 0.88 5.62 0.089
Left MBCA 0.66 0.42 1.04 0.075
Right CRVE 2.04 0.98 4.24 0.057
Right adjusted CRAE 0.34 0.16 0.74 0.007
Right MV asymmetry 0.61 0.38 1.00 0.049
AUC: 0.8073 (95%CI: 0.7216–0.893)

Abbreviations: CRAE, central retinal arteriolar equivalent; CRVE, central retinal venular equivalent; MBCA, bifurcation coefficient of artery; MV asymmetry, venous asymmetry index.