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. 2023 Feb 24;18(2):e0281701. doi: 10.1371/journal.pone.0281701

Table 4. Stepwise logistic regression analysis showing factors associated with obstructive coronary artery disease in different models.

OR 95% CI for OR P-value
Lower Upper
Model 1: Inclusion of traditional cardiovascular risk factors only
Age ≥55 years 7.39 2.28 24.01 0.001
Dyspnea 3.20 1.04 9.79 0.042
AUC: 0.7774 (95%CI: 0.6777–0.8771)
Model 2: Inclusion of retinal characteristics only
Left MBCV 2.60 1.30 5.20 0.007
Left AVR 1.11 1.03 1.20 0.006
Right MBCA 0.14 0.05 0.42 < .001
Right AF 2.97 1.03 8.54 0.044
Right Tortuosity 0.39 0.17 0.92 0.030
Right A occlusion 2.91 1.17 7.27 0.022
AUC: 0.9022 (95%CI: 0.8098–0.9946)
Model 3: Inclusion of traditional cardiovascular risk factors and retinal characteristics retinal characteristics
Dyspnoea 5.82 1.03 32.95 0.047
Left MBCV 2.36 1.14 4.87 0.020
Left AVR 1.11 1.03 1.21 0.011
Right MBCA 0.16 0.05 0.50 0.001
Right AF 3.27 1.05 10.17 0.041
Right Tortuosity 0.34 0.13 0.86 0.023
Right A occlusion 2.96 1.17 7.49 0.022
AUC: 0.9168 (95%CI: 0.8420–0.9917)

Abbreviations: MBCA, bifurcation coefficient of artery; MBCV, bifurcation coefficient of venule; AF, atrial fibrillation; Tortuosity, Tortuosity; A occlusion, Arteriole occlusion; AVR, Arteriole-venule ratio.