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Phylogenetic conservation (h, human; m, murine; r, rat; ch, chicken; p, porcine) of destruction boxes in p105, in IκBα,-β, and -ɛ, in β-catenin, and in HIV-1 Vpu. Position numbers of the critical serine residues in the respective full-length proteins are indicated. Serines where stimulated phosphorylation has been shown experimentally are underlined.
