Did you experience any AET side effect? Yes—no. What side effects did you experienced? Open answer. How would you define your side effects? Mild—moderate—severe.

4.Have you ever considered to discontinue AET because of side effects? Yes—no. 5.Have you ever taken therapy irregularly because of side effects? Yes—no. 6.Have you ever changed your AET because of side effects? Yes- no. If yes, what? Open answer. Did you notice any improvement? Yes—no. 7.Did you stop AET because of side effects? Yes—no. If yes, when? Open answer. Did you stop therapy by yourself or under medical supervision? By myself—under medical supervision.

8.After the first 5 years of AET, was extended therapy suggested to you? Yes—no. If yes, did you accept? Yes—no. 9.Did you experience different or worse side effects during extended therapy? Yes—no. If yes, what? Open answer. 10.Did you stop extended therapy before 10 years of treatment because of side effects? Yes—no. If yes, when did you stop and why? Open answer. 11.If you did not accept extended therapy, it was because of side effects? Yes—no.

12.Have you ever talked to your gynecologist about these problems? Yes—no. 13.Have you ever taken any medication to overcome these symptoms? Yes—no. If yes, what? Open answer. Did you get relief? Yes—no. 14.If you had received more information about side effects by your gynecologist, would you have continued AET? Yes—no. 15.If you had received an effective therapy against your symptoms, would you have continued AET? Yes—no.

16.Have you ever used the menopause service of the Breast Unit? Yes—no. If yes, did you find it useful? Yes—no. Would you recommend it? Yes—no. 17.Have you ever received psychological support? Yes—no. If yes, did you find it useful? Yes—no. Would you recommend it? Yes—no. 18.Did you felt well supported by medical staff during your therapy? Yes—no.