Table 2.
Authors | SBRT Dose | Median Follow-Up [Months] | Local Control at 2 Years |
Overall Survival at 2 Years | Toxicity (Grade 3+) |
---|---|---|---|---|---|
Kimura et al. [11] | 40 Gy/5 fr | 20.8 | 90% | 84% | 11% |
Yoon et al. [12] | 45 Gy/3 fr | 47.8 | 100% | 96% | 4% |
Durand–Labrunie et al. [13] | 45 Gy/3 fr | 48 | 94% | 69% | 31% |
Jang et al. [14] | 45–60 Gy/3 fr | 41 | 97% | 84% | 3% (1 year) |
Park et al. [15] | 30–60 Gy/3 fr | 38.2 | 91.3% (5 years) | 44.9% (5 years) | 2.8% |
Kim et al. [16] | 36–60 Gy/4 fr | 27 | 25–94% | 81.3% | 28% |
Takeda et al. [17] | 35–40 Gy/5 fr | 41.7 | 96.3% (3 years) | 66.7% (3 years) | 8.9% |
Lasley et al. [18] | 48 Gy/3 fr (CP-A), 40 Gy/3 fr (CP-B) |
33.3 (CP-A), 46.3 (CP-B) |
91% (CP-A), 82% (CP-B) |
72% (CP-A), 32.7% (CP-B) |
11% (CP-A), 38% (CP-B) |
Bujold et al. [19] | 24–56 Gy/6 fr | 31.4 | 87% (1 year) | MST 17 months | 10% |
Kang et al. [20] | 42–60 Gy/3 fr | 17 | 94.6% | 68.7% | 15% |
Abbreviations: fr = fraction, CP = Child–Pugh, MST = median survival time.