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. 2023 Feb 7;20(4):2903. doi: 10.3390/ijerph20042903

Table 1.

Studies supporting survival differences in women with HR+/HER2-breast cancer.

Study Patient Number Population Description Median Follow-Up Survival Measure Risk
O’Brien et al. [5] 246 Black, 379 White Carolina Breast Cancer Study 9.0 years BCSS a HR b 1.9 (95% CI 1.3–2.8)
Sparano et al. [13] 176 Black, 2803 White Randomized phase III trial 95 months BCSS HR 1.65, 95% CI 1.11–2.46
Ma et al. [4] 244 Black, 405 White Women’s CARE study 10 years BCSS HR 1.52, 95% CI 1.01–2.28)
Warner et al. [6] 365 Black, 6763 White NCCN network centers 6.2 years BCSS HR 1.76, 95% CI 1.09–2.85
Tao et al. [14] 4813 Black, 59,341 White California Cancer Registry 3.5 years BCSS HR 1.27, 95% CI 1.12–1.43
Vidal et al. [15] 521 Black, 1326 White Memphis, TN 29.9 months All-cause HR 1.87, 95% CI 1.33–2.62
Collin et al. [9] 2074 Black, 3511 White Metropolitan Atlanta 3.5 years BCSS HR 2.43, 95% CI 1.99–2.97
Zhao et al. [16] 613 Black, 1062 White Chicago Multiethnic Epidemiologic Breast Cancer Cohort 6.9 years BCSS HR 2.37, 95% CI 1.60–3.50)
Lorona et al. [11] 20,152 Black, 148,745 White SEER database 34 months BCSS HR varies by stage and age group
Zhou et al. [17] 2763 Black, 38,951 White SEER−Medicare Linked Database 7 years Breast cancer recurrence Subdistribution HR 1.27, 95% CI 1.15–1.40
Albain et al. [8] 693 Black, 8189 White TAILORx Trial 90 months DFS c HR 1.28, 95% CI 1.05–1.57
Sadigh et al. [12] 693 Black, 8189 White TAILORx Trial 96 months RFS d HR 1.39, 95% CI 1.05–1.84
Du [10] 27,279 Black, 211,344 White SEER database BCSS HR 1.21, 95% CI 1.06–1.37

a BCSS = breast cancer-specific survival; b HR = hazard ratio; c DFS = disease-free survival; d RFS = recurrence-free survival.