Table 1.
Publicly available human plasma miRNA expression data were assessed for haemolysis using the DraculR method, identifying multiple samples in each dataset that had sufficient evidence of haemolysis to recommend caution in their use. No haemolysis information was included with the original dataset.
| Dataset | Experimental Context | Total Samples | Caution | Differentially Abundant miRNA | Publication |
|---|---|---|---|---|---|
| GSE153813 | Case: Control Profile miRNA expression at each stage of menstrual cycle; endometriosis |
9 | 3 | NA | NA |
| GSE105052 | Case: Control Friedreich’s ataxia |
42 | 3 | hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, hsa-miR-142-3p | [26] |
| GSE151341 | Case: Control Early radiographic knee osteoarthritis biomarker |
91 | 4 | hsa-miR-335-3p, hsa-miR-199a-5p, hsa-miR-671-3p, hsa-miR-1260b, hsa-miR-191-3p, hsa-miR-191-5p +, hsa-miR-335-5p, hsa-miR-543 |
[27] |
| GSE118038 | Case: Control Prostate cancer biomarker |
70 | 32 | hsa-miR-4732-3p, hsa-let-7a, hsa-miR-26b-5p, hsa-miR-98-5p, hsa-miR-30c-5p *, hsa-miR-21-5p, hsa-miR-191-5p + |
[28] |
* Haemolysis-Metric-associated miRNA, DE reported in associated publication. + Haemolysis-Metric-associated miRNA, DE reported in wider literature search.