Table A4.
Enriched function using AR-co-expressed genes in both sexes.
| Source | Term_Name | Term_ID | Adjusted_p_Value | Term_Size | Query_Size | Intersection_Size | Intersections |
|---|---|---|---|---|---|---|---|
| GO:MF | extracellular matrix structural constituent | GO:0005201 | 0.001116 | 174 | 27 | 5 | FBN1, LAMA2, OGN, LTBP2, DCN |
| GO:MF | glycosaminoglycan binding | GO:0005539 | 0.009894 | 244 | 30 | 5 | FBN1, CCDC80, LTBP2, DCN, SLIT3 |
| GO:MF | heparin binding | GO:0008201 | 0.043013 | 173 | 30 | 4 | FBN1, CCDC80, LTBP2, SLIT3 |
| GO:BP | cellular response to vascular endothelial growth factor stimulus | GO:0035924 | 0.002535 | 62 | 29 | 4 | ADAMTS12, PDGFRA, DCN, JCAD |
| GO:BP | anatomical structure morphogenesis | GO:0009653 | 0.002877 | 2722 | 31 | 15 | ADAMTS12, SVEP1, FBN1, SLC12A6, LAMA2, PEAK1, FHL1, PGR, MAN2A1, AKAP13, PDGFRA, DCN, JCAD, SLIT3, CDKL5 |
| GO:BP | circulatory system development | GO:0072359 | 0.002957 | 1109 | 30 | 10 | SVEP1, FBN1, BICC1, SLC12A6, REST, AKAP13, PDGFRA, DCN, JCAD, SLIT3 |
| GO:BP | developmental process | GO:0032502 | 0.006599 | 6424 | 31 | 22 | ADAMTS12, SVEP1, FBN1, BICC1, RUNX1T1, NHSL2, SLC12A6, LAMA2, PEAK1, FHL1, REST, SELENOP, PGR, MAN2A1, TTBK2, AKAP13, PDGFRA, KAT6A, DCN, JCAD, SLIT3, CDKL5 |
| GO:BP | regulation of cellular response to vascular endothelial growth factor stimulus | GO:1902547 | 0.006771 | 23 | 29 | 3 | ADAMTS12, DCN, JCAD |
| GO:BP | system development | GO:0048731 | 0.009857 | 4369 | 31 | 18 | ADAMTS12, SVEP1, FBN1, BICC1, SLC12A6, LAMA2, REST, SELENOP, PGR, MAN2A1, TTBK2, AKAP13, PDGFRA, KAT6A, DCN, JCAD, SLIT3, CDKL5 |
| GO:BP | anatomical structure development | GO:0048856 | 0.033845 | 5836 | 31 | 20 | ADAMTS12, SVEP1, FBN1, BICC1, SLC12A6, LAMA2, PEAK1, FHL1, REST, SELENOP, PGR, MAN2A1, TTBK2, AKAP13, PDGFRA, KAT6A, DCN, JCAD, SLIT3, CDKL5 |
| GO:BP | multicellular organism development | GO:0007275 | 0.042139 | 4823 | 31 | 18 | ADAMTS12, SVEP1, FBN1, BICC1, SLC12A6, LAMA2, REST, SELENOP, PGR, MAN2A1, TTBK2, AKAP13, PDGFRA, KAT6A, DCN, JCAD, SLIT3, CDKL5 |
| GO:BP | vascular endothelial growth factor signaling pathway | GO:0038084 | 0.043128 | 42 | 29 | 3 | PDGFRA, DCN, JCAD |
| GO:BP | cell adhesion | GO:0007155 | 0.044906 | 1521 | 4 | 4 | ADAMTS12, SVEP1, FBN1, CCDC80 |
| GO:CC | extracellular matrix | GO:0031012 | 0.000983 | 565 | 18 | 6 | ADAMTS12, FBN1, CCDC80, LAMA2, OGN, LTBP2 |
| GO:CC | external encapsulating structure | GO:0030312 | 0.000993 | 566 | 18 | 6 | ADAMTS12, FBN1, CCDC80, LAMA2, OGN, LTBP2 |
| GO:CC | basement membrane | GO:0005604 | 0.001726 | 99 | 9 | 3 | FBN1, CCDC80, LAMA2 |
| GO:CC | collagen-containing extracellular matrix | GO:0062023 | 0.002734 | 429 | 27 | 6 | FBN1, CCDC80, LAMA2, OGN, LTBP2, DCN |
| HP | Microspherophakia | HP:0030961 | 0.045002 | 3 | 18 | 2 | FBN1, LTBP2 |