Table 1.
Initial characteristics of the wounds and the health history of the patients.
| Variable | Global (n = 25) | EGF-CMC (n = 14) | CMC (n = 11) | p-Value * | |||
|---|---|---|---|---|---|---|---|
| F | RF | F | RF | F | RF | ||
| Gender | 0.656 (a) | ||||||
| Female | 7 | 28.0% | 3 | 21.4% | 4 | 36.4% | |
| Male | 18 | 72.0% | 11 | 78.6% | 7 | 63.6% | |
| Age (years) | 0.267 (b) | ||||||
| 46|―52 | 1 | 4.0% | 0 | 0.0% | 1 | 9.1% | |
| 52|―64 | 11 | 44.0% | 8 | 57.1% | 3 | 27.3% | |
| 64|―76 | 13 | 52.0% | 6 | 42.9% | 7 | 63.6% | |
| ABI classification | 0.536 (a) | ||||||
| PAD mild to moderate | 9 | 36.0% | 5 | 35.7% | 4 | 36.4% | |
| Normal | 16 | 64.0% | 9 | 64.3% | 7 | 63.6% | |
| Glycated Hemoglobin > 7% | 15 | 60.0% | 9 | 64.3% | 6 | 54.5% | 0.697 (b) |
| Injury type | 1.000 (a) | ||||||
| Diabetic | 17 | 68.0% | 9 | 64.3% | 8 | 72.7% | |
| Venous | 8 | 32.0% | 5 | 35.7% | 3 | 27.3% | |
| Injury area (cm2) | 0.727 (b) | ||||||
| 2.0|―12.0 | 16 | 64.0% | 8 | 57.1% | 8 | 72.7% | |
| 12.0|―|52.0 | 9 | 36.0% | 6 | 42.8% | 3 | 27.2% | |
| Exudate | 0.407 (a) | ||||||
| Serous | 18 | 72.0% | 9 | 64.3% | 9 | 81.8% | |
| Serosanguineous | 7 | 28.0% | 5 | 35.7% | 2 | 18.2% | |
| Exudate Amount | 0.572 (b) | ||||||
| Minimal | 8 | 32.0% | 3 | 21.4% | 5 | 45.5% | |
| Moderate | 11 | 44.0% | 8 | 57.1% | 3 | 27.3% | |
| Large | 6 | 24.0% | 3 | 21.4% | 3 | 27.3% | |
| Margin | 0.317 (b) | ||||||
| Epithelized | 15 | 60.0% | 7 | 50.0% | 8 | 72.7% | |
| Hyperkeratotic | 6 | 24.0% | 4 | 28.6% | 2 | 18.2% | |
| Maceration | 4 | 16.0% | 3 | 21.4% | 1 | 9.1% | |
| Granulation (% of bed that was covered) | 0.851 (b) | ||||||
| 1|―50 | 8 | 32.0% | 3 | 21.4% | 5 | 45.5% | |
| 51|―|100 | 17 | 68.0% | 11 | 78.6% | 6 | 54.6% | |
| Slough (% of bed that was covered) | 0.317 (b) | ||||||
| 0|―25 | 17 | 68.0% | 9 | 64.3% | 8 | 72.7% | |
| 26|―|100 | 8 | 32.0% | 5 | 35.7% | 3 | 27.3% | |
| Time of injury (months) | 0.809 (b) | ||||||
| Up to 6 months | 4 | 16.0% | 1 | 7.1% | 2 | 18.2% | |
| 7|―59 | 10 | 40.0% | 6 | 42.9% | 5 | 45.4% | |
| 60|―|480 | 11 | 44.0% | 7 | 50.0% | 4 | 36.4% | |
* Tests comparing variable distributions in control and intervention groups: (a) Fisher’s exact test; (b) Mann–Whitney test. Abbreviations: F: absolute frequency; RF: relative frequency; ABI: ankle–brachial index; PAD: peripheral obstructive arterial disease.