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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Molecular structure of ROCK 1 and ROCK 2. They are similar and both contain a kinase domain, coiled-coil region, rho-binding domain, putative pleckstrin homology domain (PHD) and cysteine-rich domain (CRD). Rho GEF = Rho guanine nucleotide exchange factor. Created with BioRender.com.