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. Author manuscript; available in PMC: 2023 Feb 28.
Published in final edited form as: Compr Physiol. 2023 Jan 30;13(1):4387–4407. doi: 10.1002/cphy.c220020

Table 1.

The Correlation Between Levels of Endotrophin and Diseases

Disease Correlation Tissue/Serum/Plasma References

Obesity and diabetes Positive Adipose tissue Sun et al. (243)
Renal fibrosis Positive Kidney Rasmussen et al. (211)
Type 2 diabetes Positive Serum Karsdal et al. (112)
Chronic kidney disease Positive Serum Fenton et al. (56)
Breast cancer Positive Plasma Bu et al. (22)
Heart failure Positive Serum Eruzun et al. (54)
Hepatocellular carcinoma Positive Tumor-neighboring regions Lee et al. (138)
Cirrhotic patients with hepatocellular carcinoma Positive Plasma Leeming et al. (145)
Obese children Positive Plasma Ezzati-Mobaser et al. (55)
Chronic obstructive pulmonary disease (COPD) Positive Serum Rønnow et al. (215)
Non-alcoholic fatty liver disease Positive Serum Kim et al. (117)
Atherosclerotic Positive Atherosclerotic plaque Holm Nielsen et al. (91)
Acute-on-chronic liver failure Positive Plasma Kerbert et al. (115)
Nonalcoholic steatohepatitis Positive Serum Hagström et al. (76)
Chronic multimorbidity Positive Serum Staunstrup et al. (238)
Polycystic ovary syndrome (PCOS) Positive Serum Guney et al. (72)
Crohn’s disease Positive Serum Lindholm et al. (154)
Diabetic nephropathy Positive Serum Yoldemir et al. (281)
Chronic kidney disease Positive Serum Sparding et al. (235)
Kidney fibrosis Positive Serum Genovese et al. (66)
Fibrotic interstitial lung diseases Positive Serum Dasdemir Ilkhan et al. (44)
Kidney transplantation Negative Pretransplant plasma endotrophin Tepel et al. (250)