Table 1.
Participant Demographics
| Covariate | Overall (n=647) |
ALS cases (n=381) |
Controls (n=266) |
P-Value |
|---|---|---|---|---|
| Age at survey consent (years) | 63.3 (56.5–69.9) | 64.9 (57.6–71.4) | 61.3 (55.2–68.2) | <0.001 |
| Sex | 0.143 | |||
| Female | 317 (49.0) | 177 (46.5) | 140 (52.6) | |
| Male | 330 (51.0) | 204 (53.5) | 126 (47.4) | |
| Last contact event | NA | |||
| Death | 251 (64.9) | NA | ||
| Censored | 130 (34.1) | NA | ||
| Original and/or Revised El Escorial criteria | NA | |||
| Possible/Suspected | 53 (13.9) | NA | ||
| Probable, LS | 104 (27.3) | NA | ||
| Probable | 123 (32.3) | NA | ||
| Definite | 101 (26.5) | NA | ||
| Onset segment | NA | |||
| Bulbar | 113 (29.7) | NA | ||
| Cervical | 126 (33.1) | NA | ||
| Lumbar | 142 (37.3) | NA | ||
| Time between symptom onset and diagnosis (years) | 1.01 (0.64–1.66) | NA | NA |
For continuous variables, median (25th – 75th percentile); for categorical variables, N (%). P-values for continuous and categorical variables correspond to analysis of variance tests and chi-squared tests, respectively.
ALS, amyotrophic lateral sclerosis; LS, laboratory supported; NA, not applicable.