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. 2022 Oct 21;113(3):643–659. doi: 10.1002/cpt.2749

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© 2022 The Authors. Clinical Pharmacology & Therapeutics published by Wiley Periodicals LLC on behalf of American Society for Clinical Pharmacology and Therapeutics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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African geographical regions represented in the study. The size of the circles (not drawn to scale) reflect the relative number of participants from each population group. AWI‐Gen, Africa Wits‐INDEPTH partnership for Genomics studies; CBRL, Cell Biology Research Laboratory (National Institute of Communicable Diseases, Wits University, Johannesburg); DRC, Democratic Republic of the Congo; H3Africa, Human Heredity and Health in Africa Consortium; SAHGP, Southern African Human Genome Programme.