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. 2022 Oct 21;113(3):643–659. doi: 10.1002/cpt.2749

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© 2022 The Authors. Clinical Pharmacology & Therapeutics published by Wiley Periodicals LLC on behalf of American Society for Clinical Pharmacology and Therapeutics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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CYP2D6 phenotype distribution across the SSA populations in the study. BFA, participants from Burkina Faso; BOT, participants from Botswana; BRN, Berom in Nigeria; BSZ, Bantu‐speakers in Zambia; CAM, Cameroonian participants; ESN, Esan in Nigeria; FNB, Fon in Benin; GHA, Ghanaian participants; GWD, Gambian (Mandinka) in Western Divisions of the Gambia; LWK, Luhya in Webuye (Kenya); MSL, Mende in Sierra Leone; SA, South African participants (south eastern Bantu‐speakers); SSA, sub‐Saharan African; YRI, Yoruba in Ibadan, Nigeria.