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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Shock. 2022 Oct 21;59(2):239–246. doi: 10.1097/SHK.0000000000002019

Figure 2. Impacts of neutrophil subtypes and their mechanisms of action.

Figure 2.

Different subtypes of neutrophils (pro-inflammatory or immune suppressive) produce different mediators and directly interact with lymphocytes to promote organ injury and death in sepsis. APN, antigen presenting neutrophils; RMN, reverse-migrated neutrophils; LDN, low-density neutrophils; OLFM4, olfactomedin 4; Siglec-F, sialic-acid-binding immunoglobulin-like lectin-F; NE, neutrophil elastase; ROS, reactive oxygen species.