Table 1:
Markers of neutrophil subtypes.
| Subtypes | Markers | References |
|---|---|---|
| N1 | TNF-α, Fas, ICAM-1, CCL3 | 19 |
| N2 | Arginase, CCL2, CCL5 | 19 |
| Nreg | PD-L1, IL-10Rβ, TNF-α, TGF-β1, IRF5, TLR2 | 18 |
| Aged | CXCR4, CD62Llo, ICAM-1 | 16, 26 |
| APN | MHC-II, CD40, CD64, CD83, CD86 | 31-34 |
| RMN | ICAM-1, CXCR1lo | 17 |
| ICAM-1+ | iNOS, MPO | 24 |
| LDN | CD11bhi, CXCR4, ICAM-1, iNOS | 42 |
| OLFM4+ | CD64lo | 63 |
| Siglec-F+ | TNF-α, ICAM-1, PPIA, ProTα | 64 |
APN, antigen presenting neutrophils; RMN, reverse-migrated neutrophils; LDN, low-density neutrophils; OLFM4, olfactomedin 4; Siglec-F, sialic-acid-binding immunoglobulin-like lectin-F; CCL, CC chemokine ligand; CXCR, CXC chemokine receptors; IRF5, interferon regulatory factor 5; iNOS, inducible nitric oxide synthase; PPIA, peptidylprolyl isomerase A; ProTα, prothymosin alpha; iNOS, inducible nitric oxide synthase; MPO, myeloperoxidase.