Table 3:

Comparison of cytokine levels between controls without CF (n=20) and pwCF (n=48) at baseline, and between pwCF at baseline and 6-months post-ETI

	Control (at baseline)	pwCF (at baseline)	pwCF 6-months post-ETI	Control vs pwCF at baseline1	pwCF at baseline vs. 6-months post-ETI2
	Mean (pg/mL)±SD			p	p
IL-22	0.2 ±0.2	0.7 ±0.2	0.4 ±0.3	0.097	0.256
IL-23	0.9 ±0.7	1.8 ±3.9	2.1 ±5.8	0.167	0.595
IFN-γ	3.7 ±2.4	4.7 ±5.7	4.9 ±4.8	0.283	0.838
IL-4	0.04 ±0.02	0.1 ±0.3	0.1 ±0.2	0.186	0.465
IL-6	0.4 ±0.2	1.2 ±1.3	0.6 ±0.9	<0.001*	0.002*
IL-8	2.1 ±0.9	3.8 ±3.1	2.6 ±1.8	0.001*	0.004*
IL-10	0.2 ±0.2	2.1 ±6.7	2.5 ±8.4	0.056	0.214
IL-13	2.3 ±1.2	1.2 ±1.3	1.2 ±1.4	0.001*	0.688
IL-17A	0.6 ±0.2	1.8 ±1.3	1.3 ±1.0	<0.001*	0.004*

¹independent t-test,

²paired t-test

^*p ≤ 0.05