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Immunohistochemistry for tau and phosphorylated tau epitopes in mice injected with AAV9 viral vectors expressing tauwild-type, tauP310L or tauR406W. Horizontal sections were stained for HT7 (total tau; panels A-C), AT8 (labeling tau phosphorylated at residues 199 and 202; Panels D-F) and an antibody recognizing tau phosphorylated at residue 396 (panels G-I). Scale bar = 1 mm.
